ABSTRACT
A process is dened as enantioselective when one enantiomer of a chiral compound is formed or destroyed in preference to the other enantiomer. Since enantiomers have the same physicochemical properties in isotropic conditions, enantioselectivity shows up only in reactions occurring in anisotropic conditions, i.e., when the chiral compound interacts either with a dissymetric selector to form a diastereomeric pair or with circularly polarized electromagnetic radiations. The ability of the dissymetric probe to differentiate between two enantiomers of a chiral molecule is particularly important in biochemistry1,2 and organic synthesis.3 An enantioselective reaction yields an optically active product from achiral starting materials, using either a chiral catalyst, an enzyme, or a chiral reagent. The degree of selectivity is measured by the enantiomeric excess. An important variant is kinetic resolution, in which a preexisting chiral center undergoes reaction with a chiral catalyst, an enzyme, or a chiral reagent such that one enantiomer reacts faster than the other and
6.1 Introduction .....................................................................................................87 6.2 Experimental Methodologies .......................................................................... 89 6.3 Chiral Ion Recognition ....................................................................................90
