ABSTRACT
Cryosurgery, sometimes referred to as cryotherapy or cryoablation, is the use of extreme cold produced by cryogenic agents to destroy abnormal or diseased tissues. e application of cryosurgery includes treatment of many kinds of cancer and some noncancerous diseased tissues. Good results have been achieved in
CONTENTS
7.1 Introduction 221 7.2 Experimental Procedures 223
7.2.1 Phantom Study 223 7.2.2 In Vitro Tissue Study 226
7.3 Numerical Modeling 228 7.4 Results and Discussion 231
7.4.1 Experimental Results 231 7.4.1.1 Phantom Experiments 231 7.4.1.2 In Vitro Tissue Experiments 240
7.4.2 Numerical Results 247 7.5 Conclusions 253 Acknowledgments 253 References 255
cryosurgical treatment of many types of tumors [1]. However, local recurrences at the site of ablation close to large blood vessels have been reported at rates from 5% to 44% or even higher [2,3]. In order to perform a successful cryosurgery for tumors embedded with large blood vessels, it is very necessary to understand the eects of large vessels on the temperature responses of biological tissues subjected to freezing [4-6].
