ABSTRACT

Cytogenetics is a relatively young science. The correct number of chromo­ somes in humans was established less than 50 years ago ( 1 ) . The current explosion of knowledge in the field of human and medical genetics is aston­ ishing, with discoveries being made monthly and sometimes weekly. Pro­ gress has accelerated in the last few years, as a result of the advent of the Human Genome Project, whose goals include mapping all of the estimated 50,000 to 1 00,000 human genes and sequencing the estimated 3 billion nu­ cleotides in a haploid set of chromosomes. In this chapter we trace the history of cytogenetics in a nonsystematic, somewhat nostalgic fashion.