The low-density lipoproteins (LDL), are pseudomicellar, quasispherical particles which constitute the major vehicle for cholesterol transport in human plasma; they consist essentially of cholesterol in both esterified and non-esterified forms, phospholipids, minor amounts of triacylglycerols, and a highly specialised protein component of hepatic origin, apolipoprotein B100 (apo.B100).