ABSTRACT

Lyme disease, or erythema chronicum migrans, is a multisystemic infection caused by Borrelia burgdorferi and transmitted to humans by a tick vector of the genus Ixodes. It affects the skin, joints, heart and the nervous system. It has an early phase which is manifested by migratory erythema, disseminated secondary lesions and Iymphocytoma, and a later phase with atrophic chronic acrodermatitis and sclerodermiform lesions.