ABSTRACT
Granuloma inguinale (GI) or donovanosis is a chronic, granulomatous disease that affects the skin of the anogenital and inguinal regions. It is usually acquired by sexual contact and is characterized by ulcers that are moderately painful and progressively destructive. It is the least common of the venereal diseases. It is a sexually transmitted disease (STD) in which malignant transformation can be observed when diagnosed in young individuals. Its relation to penile cancer is unclear. Because it causes ulcerous lesions, its control constitutes a method to decrease the transmission of HIV ( Genitourin Med 1995; 71:27-31). Recently singledose treatment with antibiotics has been successful.
