ABSTRACT
Tinidazole, 1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole, is a nitroimidazole drug similar to metronidazole (see Chapter 99, Metronidazole). It was synthesized in 1969 and it has an in vitro activity profile similar to that of metronidazole, including efficacy against Trichomonas vaginalis (Miller et al., 1969; Howes et al., 1970). Tinidazole is useful for the treatment of protozoal parasitic infections (Giardia lamblia [G. intestinalis], Entamoeba histolytica) and against anaerobic bacterial infections.
