Norfloxacin

Norfloxacin (Noroxin) was synthesized at the Kyorin Central Research Laboratory in Japan (Ito et al., 1980). It is a fluorinated quinolone carboxylic acid derivative with a molecular weight of 319.34 and has the chemical formula 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid. Its empirical formula is C₁₆H₁₈FN₃O₃. The structure of norfloxacin is shown in Figure 102.1. Figure 102.1 Structure of norfloxacin. https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9781315152110/08d8042d-9481-4a8d-8c27-9bd589f6de6b/content/fig102_1.tif" xmlns:xlink="https://www.w3.org/1999/xlink"/>