ABSTRACT

Ofloxacin is a fluoroquinolone antibiotic first synthesized at Daiichi Pharmaceutical Company, Japan, in 1980. It has the chemical formula 9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-(1,2,3-de)1,4-benzoxazine-6-carboxylic acid (Sato et al., 1982; Kumazawa and Yagisawa, 2002). The chemical structure of the compound is shown in Figure 103.1 (Sato et al., 1982). Chemical structure of ofloxacin. https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9781315152110/08d8042d-9481-4a8d-8c27-9bd589f6de6b/content/fig103_1.tif" xmlns:xlink="https://www.w3.org/1999/xlink"/>