ABSTRACT
Enoxacin is a second-generation fluoroquinolone. It has the chemical formula l-ethyl-6-fluoro-I, 4-dihydro-4-oxo-7 piperazinyl)-I, 8-naphthyridine-3-carboxylic acid (see Figure 112.1). Overall, the in vitro activity of enoxacin is comparable with that of norfloxacin or lomefloxacin (see Chapter 102, Norfloxacin, and Chapter 116, Lomefloxacin) but inferior to those of other fluoroquinolones, such as ciprofloxacin (see Chapter 101, Ciprofloxacin) and moxifloxacin (Bauernfeind and Ullmann, 1984; Chin and Neu, 1983; Guimaraes and Noone, 1986; Henwood and Monk, 1988; Ismaeel and Tayeb, 1993; Reeves et al., 1984; Siporin and Towse, 1984; Weinstein, 1988; see Chapter 105, Moxifloxacin). Chemical structure of enoxacin. https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9781315152110/08d8042d-9481-4a8d-8c27-9bd589f6de6b/content/fig112_1.tif" xmlns:xlink="https://www.w3.org/1999/xlink"/>
