ABSTRACT
Rifaximin (4-deoxy-4′-methylpyrido[1′,2′-1,2]imidazole-[5,4c]-rifamycin SV) is a synthetic antimicrobial and derivative of rifamycin (Jiang and DuPont, 2005; Scarpignato and Pelosini, 2005; Finegold et al., 2009). It was first described as compound L-105 in 1982 and marketed in Italy in 1987 (Huang and DuPont, 2005; Scarpignato and Pelosini, 2005). Its empirical formula is C43H51N3O11 and its molecular weight is 785.9 Da; the chemical structure is shown in Figure 128.1. Chemical structure of rifaximin. https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9781315152110/08d8042d-9481-4a8d-8c27-9bd589f6de6b/content/fig128_1.tif" xmlns:xlink="https://www.w3.org/1999/xlink"/>
