ABSTRACT

Ampicillin–sulbactam (AMP/S) is a beta-lactam/beta-lactamase inhibitor that was developed to overcome the increasing resistance of various bacteria to ampicillin. AMP/S is marketed under various trade names, such as Unasyn and Begalin. It is an antibacterial combination of the semisynthetic antibiotic ampicillin sodium (see Chapter 5, Ampicillin and amoxicillin) and the beta-lactamase inhibitor sulbactam sodium (see Chapter 13, Beta-lactamase inhibitors).