ABSTRACT
Mefloquine is available as a hydrochloride salt of the structure depicted in Figure 178.1 (Roche, 2003a). Its official chemical name is (R*, S*)-(±)-α-2-piperidnyl-2,8-bis (trifluromethyl)-4-quinolinemethanol hydrochloride (Roche, 2003a). Mefloquine is a white crystalline solid with a molecular weight of 418 (Roche, 2003a). The compound has two chiral centers, and there are four isomeric forms. The commercially available formulation is a racemate of the 11R,2′S and 11S,2′R enantiomers. Chemical structure of mefloquine. https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9781315152110/08d8042d-9481-4a8d-8c27-9bd589f6de6b/content/fig178_1.tif" xmlns:xlink="https://www.w3.org/1999/xlink"/>
