ABSTRACT

Diloxanide furoate is a luminal amebicide first synthesized in 1956 and marketed primarily under the brand name Furamide by Boots in the United Kingdom. It is now not commercially available in most countries in this form (including Australia, Canada, and the United States). Diloxanide is marketed as diloxanide furoate, which is the ester of 2-furoic acid and diloxanide, a dichloroacetamide derivative with a relatively simple structure (Figure 190.1). It has also been marketed by Abbott as Entamizole, a co-formulation that contains diloxanide furoate combined with metronidazole. Chemical structure of diloxanide and diloxanide furoate. https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9781315152110/08d8042d-9481-4a8d-8c27-9bd589f6de6b/content/fig190_1.tif" xmlns:xlink="https://www.w3.org/1999/xlink"/>