ABSTRACT
The most commonly used first-generation cephalosporins are the parenteral cephalosporins, cefazolin and cephalothin (see Chapter 18, Cephalothin and cefazolin), and the oral drug, cephalexin (See Chapter 19, Cephalexin). However, a number of other first-generation cephalosporins have been available for clinical use in some countries, although are rarely used now. These include cefadroxil, cephradine, cephapirin, cephacetrile, cephaloridine, cephaloglycin, cephalonium, cefatrizine, cefazaflur, cefazedone, cefroxadine, and cephtazole. Specific comments will be made about some of these first-generation cephalosporins.
