ABSTRACT
Maraviroc was synthesized by Pfizer as UK-427,857 (4, 4-difluoro-N-[(1S)-3-[exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabi-cyclo[3.2.1]oct-8-yl]-1-phenylpropyl] cyclohexanecarboxamide) (Dorr et al., 2005; Wood and Armour, 2005). The molecular weight of maraviroc is 514, and its chemical structure is shown in Figure 253.1. Chemical structure of maraviroc. https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9781315152110/08d8042d-9481-4a8d-8c27-9bd589f6de6b/content/fig253_1.tif" xmlns:xlink="https://www.w3.org/1999/xlink"/>
