ABSTRACT

Cefixime is an orally administered cephalosporin with a broader antimicrobial spectrum than those of earlier oral cephalosporins, such as cephalexin and cefaclor. It is referred to as a third-generation oral cephalosporin, but its spectrum of activity is not quite as wide as those of other oral third-generation cephalosporins (e.g. cefpodoxime) or parenteral third-generation cephalosporins (e.g. cefotaxime) (Anonymous, 1989). Its molecular weight is 453. Its chemical structure is shown in Figure 29.1.