ABSTRACT

Fosfomycin is a phosphoenolpyruvate analog produced by Streptomyces fradiae and by some Pseudomonas species but is now mostly obtained synthetically. It is a broad-spectrum antibiotic with bactericidal properties (Hendlin et al., 1969). It is a rather small molecule compared with other classic antibiotics, with a molecular weight of 138; its molecular structure is shown in Figure 79.1. Molecular structure of fosfomycin trometamol. https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9781315152110/08d8042d-9481-4a8d-8c27-9bd589f6de6b/content/fig79_1.tif" xmlns:xlink="https://www.w3.org/1999/xlink"/>