ABSTRACT
Dapsone (4,4′-diaminodiphenylsulfone; DDS) is a sulfone that was the first effective antimicrobial for the treatment of leprosy. It has since been found useful in the treatment and prevention of malaria, Pneumocystis jiroveci infection, and Toxoplasma gondii infection. Its immunomodulatory effects have been found beneficial in a number of noninfective dermatologic and other inflammatory disorders.
