ABSTRACT

If this motion is not accounted for during imaging, planning, and delivery of radiotherapy, geometric errors will occur in the beam-target alignment, leading to dosimetric errors. Dosimetric errors are a double-edged sword-missing the tumor means hitting normal tissue with higher-than-planned doses. A lower dose to the tumor means a lesser chance of local tumor control and potentially metastatic control, whereas a higher dose to normal tissue means a higher chance of acute and late treatmentrelated toxicity.