ABSTRACT
The early symptoms and signs are numbness and tingling sensation in toes or sole of foot, like the feeling of walking in the gravel with bare foot. These symptoms progress and intermittent claudication occurs. As the disease continues to deteriorate, toes become cyanotic change and if infection, such as paronychia superimposing on the ischemic toes or foot, then skin discoloration quickly developed and become gangrenous change. If it is a wet gangrene, then it could spread proximally to the higher level. Another type of gangrene is dry gangrene which is characterized by the mummification of the affected toes or foot. This is the late stage and patient will suffer from excruciating pain and needs narcotics for relief. To make a diagnosis of BFD is on the basis of history and clinical presentation. The laboratory data are non-specific.
