ABSTRACT
Since the interactions between arti‹cial biomaterial and biological tissues occur mainly at their interface, the surface properties of biomaterials such as topography, roughness, chemistry, and physical characteristics exert a large in¢uence on their biological response. On the other hand, nanomaterials can mimic the surface properties (including topography, energy,
CONTENTS
Introduction ................................................................................................................................. 203 Titania ........................................................................................................................................... 204 Fabrication and Characterization of Nanostructured Titania Coatings .............................. 205
Fabrication of Titania Nanotube Arrays ............................................................................. 205 Equipment for Anodization ............................................................................................. 205 Background of Titania Nanotubes .................................................................................. 205 Mechanism of Nanotube Array Formation ................................................................... 207 Geometry Control of Titania Nanotube Arrays ............................................................ 210 Structure Characterization of Titania Nanotube Arrays .............................................. 210
Biological Performance and Applications .......................................................................... 214 Cell Response to Titania Nanotubes ............................................................................... 214 Bioactivity/Bone Conductivity ....................................................................................... 215 Drug Delivery .................................................................................................................... 216
Fabrication of Nanoporous Titania Coatings .................................................................... 220 Fabrication of Interconnected Porous Coating .............................................................. 220 Nanonetworked Titania Coatings ...................................................................................222
