ABSTRACT

Current techniques for the treatment of musculoskeletal disorders can be limited by the availability, quality, and quantity of materials, such as grafts to perform surgical repair. This has led to the exploration and development of novel methods of intervention based on tissue engineering and regenerative medicine. Stem cells, due to their ability to differentiate toward various lineages, may serve as an important tool in regenerative medicine and tissue engineering, supported by experimental and clinical data. This chapter reviews the applications for stem cells in the musculoskeletal system (bones, joints, and soft tissues).