ABSTRACT
Introduction Cyclamate (Figure 7.1) was synthesized in 1937 by a University of Illinois graduate student, Michael Sveda, who accidentally discovered its sweet taste (Audrieth and Sveda 1944). e patent for cyclamate (US Patent 1942) eventually became the property of Abbott Laboratories, which
Contents Introduction .............................................................................................................................. 93 Production ................................................................................................................................ 94 Physical Characteristics ............................................................................................................. 95 Relative Sweetness and Utility ................................................................................................... 95 Admixture Potential ................................................................................................................ 100 Technical Qualities .................................................................................................................. 100 Utility ......................................................................................................................................101 Availability ...............................................................................................................................102 Shelf Life ..................................................................................................................................102 Transport..................................................................................................................................103 General Cost/Economics ..........................................................................................................103 Metabolism ..............................................................................................................................103 Carcinogenicity ........................................................................................................................105 Mutagenicity ............................................................................................................................107 Other Toxicity ..........................................................................................................................107
