ABSTRACT
In an RCT, patients may have either a preference for the standard treatment or the new treatment being evaluated or may be indifferent to both treatments. If patients with preferences consent to be randomized, then some patients will get their preferred treatment and others will not. It is hypothesized that participants who receive their preferred treatment might be better motivated and comply better with the treatment programs and report better outcomes [3], whereas patients who do not receive their preferred treatment
CONTENTS
11.1 Introduction ................................................................................................ 131 11.2 Evidence for the Effects of Patients’ Preferences in Randomized
Controlled Trials ........................................................................................ 132 11.3 Fully Randomized Preference Trial ........................................................ 133
11.3.1 When to Use This Type of Design ............................................... 134 11.3.2 Collecting Preference Data ........................................................... 134 11.3.3 Advantages and Disadvantages of the Fully Randomized
Preference Trial .............................................................................. 134 11.3.4 Statistical Analysis in Fully Randomized Preference Trials.......135
