ABSTRACT

A material placed in or contacting with a biological system causes various extent of interfacial interaction with biological components that constitute the contacting biological surface. The extent of the interfacial interaction determines the overall perturbation to the host biological system. If the extent is greater than the tolerance limit of the host biological system, it is generally conceived that the material is not biocompatible. If the level of perturbation caused by the interfacial interaction is within the tolerance limit, the material could be tolerated by the host biological system[1]; in such a situation, the material could be viewed, in practical sense, as “biocompatible.”