ABSTRACT

Y. IKEDA !•*, T. HIRAIl, T. MAKIURA], T. TERASAWA1 and N. HAMAUE 2

Department of Prosthodontics, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido 061-0293, Japan Department of Pharmacology, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido 061-0293, Japan

Abstract-In order to verify the influence of tooth loss and brain function in the rat, Wistar male aged rats were divided into the following groups: a control group (fed with solid diet), a soft diet group (fed with powder diet containing the same components as solid one), and a molar-crownless group (all molars were removed at 25 weeks and then fed with a powder diet.