ABSTRACT
MOHAMMAD SAEEDl<*, PHILIPPE M. FROSSARD1 and HASAN S.PARVEZ2 1 Department of Biological and Biomedical Sciences, The Aga Khan University, Stadium Road, Karachi 74800, Pakistan Developmental Neuroendocrinology and Neuropharmacology Unit, Institute Alfred Fessard for Neurosciences, CNRS, Gif sun Yrelte, France
Abstract-Alzheimer's disease (AD) is the most common cause of dementia worldwide. It causes major debility for the elderly with medical, social and economic implications. The pathology of AD was described in early twentieth century. Significant scientific progress has been made to date in understanding the pathophysiology and genetics as well as developing therapeutic strategies for slowing disease progression and providing symptomatic relief to AD patients. This chapter reviews these advances and explores the links, molecular genetics and cellular biology has provided us today to tackle this devastating disorder.
