ABSTRACT
Abstract In this work, we performed a systematic study of femtosecond laser-induced surface structures on platinum and their effects on both hydrophobicity and fibroblast cell proliferation. Our finding is that the femtosecond laser-induced surface structures suppress the fibroblast cell proliferation. This finding provides a way for controllably inhibiting fibroblast proliferation that is important in a variety of biomedical applications. Another finding is that there is a clear correlation between the femtosecond laser-induced hydrophobicity and cell growth: the higher the hydrophobicity, the lower the cell proliferation. This indicates that wettability tests can be a suitable technique for the prognosis of cell response to textured biomaterials.
