The VA National Center for Patient Safety (NCPS) evaluated the impact of culture, age, and education on the understanding of a proposed evidence-based VA prescription label. The evaluation was completed through a structured in-person focus group questionnaire process. Participants were recruited from various regions around the United States to ensure broad representation of various cultural and ethnic groups. The study confirmed that a new standardized VA prescription label is preferred by Veterans and improves Veteran comprehension of prescription label information.