The anticipated increase in the world population, people’s desire to live at home for as long as possible and the shortage of health-care professionals make the need to develop technological supports for people with chronic yet manageable conditions to monitor and take care of their own health. In our work in the Smart Condo™, we are developing a sensor-based infrastructure for non-intrusively monitoring and analyzing the activities of people at home. In this paper we review our technology and research methodology and we report on the findings of a case study with two participants.