ABSTRACT
This chapter discusses the studies on the elucidation of potential and impact of nanotoxicity associated with nanomaterials in nanobiotechnology. The reason for this may be that the translocation ability of nanoparticles is partially dependent on the particle size and solubility. The nature and intensity of biological effects of nanoparticles depend on their physicochemical characters such as size, chemical composition, surface structure, solubility, shape, and how the individual nanoparticles accumulate together. The following improvement of our understanding of the nanotoxicity mechanisms will enable a safer development of nanotechnology in the future. Facing the unprecedented growth of nanotechnology in this century, it is clear that we must focus more attention to nanotoxicity potentials to minimize the risk and maximize the benefit. Nanobiotechnology focuses on the biological effects and applications of nanoparticles that include drug encapsulation, nanotherapeutics, vaccine development, biocatalysis, materials science, and synthetic biology.
