ABSTRACT
Large amounts of microarray gene expression data have been generated/collected using a variety of platforms, from different laboratories, under different conditions. Suitable analysis of such data can lead to better understanding of diseases, and better ways to diagnose and treat diseases. However, during microarray data collection processes, several factors, including platform difference (due to variation of probe sequences targeted by different platforms) and laboratory condition difference, may affect the consistency of the collected data. The consistency of microarray data, with respect to various technology platforms and laboratory conditions, needs to be evaluated before data analysis results from microarray data can be successfully and reliably applied in biological/clinical practices and regulatory decision-making.
