ABSTRACT
Most clinical and preclinical PET scans are now done in 3D mode ( sept aless). Many modern tomographs do not even provide the option of 2D scanning. 3D PET offers a factor of 6-7 in true coincidence sensitivity over 2D PET systems for typical clinical scanners, and potentially higher sensitivity improvements if longer axial ‰eld-of-view (FOV) is built [1,2]. In the clinic, higher coincidence sensitivity translates into better statistical quality of collected data or a reduction in scanning time or administered activity of studies while maintaining similar counting statistics. For preclinical studies, ultra-high-resolution small animal imaging systems with <1.6 mm axial slice spacing are already in use [3-6]. These scanners require the sensitivity of 3D data acquisition [7].
