ABSTRACT

As analytical solutions cannot be determined, the solution is obtained by inverse optimization or inverse planning. e term inverse planning is used considering this as the opposite of the forward problem, that is, the determination of the dose distribution for a specic set of sources or SDPs and corresponding dwell times. If the positions and number of sources or of catheters and the SDPs are given aer the implantation of the catheters, we term the process postplanning. en, the optimization process to obtain an optimal dose distribution is called dose optimization. Dose optimization can be considered as a special type of inverse optimization where the positions and number of sources or catheters and the SDPs are xed.