ABSTRACT
Cancer is the uncontrolled multiplication of subtly modified or mutated normal human cells. While surgery, radiation, and chemotherapy are all commonly used to treat cancer, chemotherapy is the only option if the cancer has metastasized and spread through the body. To minimize side effects, one need cancer-specific cytotoxic drugs, including DNA-binding agents, alkylating agents, and antimetabolites that interfere with DNA replication.
