ABSTRACT

INTRODUCTION Eye care professionals (ECP) have observed and noted changes in the anterior ocular surface since the fi rst insertion of a contact lens (CL) in

1c/o Alcon SA, Avenue Louis-CasaÏ 58, CH 1216 Cointrin-Geneva, Switzerland. aE-mail: helmer.schweizer@cibavision.com bE-mail: inma.perez@cibavision.com 2Universities of Novi Sad, Serbia and Velika Gorica, Croatia. *Corresponding author

1888. These came along with visible signs and reported symptoms. The careful study of those helped to make improvements of the CLs and led to on-going innovation ever since. The initial learning curve was, no surprise, very steep.