ABSTRACT

Neuroblastoma is the commonest abdominal malignancy of childhood, the annual incidence being about six cases per million children. These tumors arise in primitive precursors of the sympathetic nervous system and consequently are seen in the adrenal medulla and sites of sympathetic ganglia. Almost one-third are detected in the first 12 months of life and a further 50 percent between the ages of 1 and 4 years. Only 5 percent occur in children over the age of 10 years.