ABSTRACT

This chapter addresses the subject of screening for breast cancer in women identified as being at high risk of the disease. The definition of screening is taken to be a test that identifies those subjects likely to have a disease from those who do not. This chapter does not, therefore, consider the issues surrounding the use of genetic testing to identify carriers of known breast cancer predisposition genes; these, together with the development of models to identify women at high risk, are considered elsewhere in this volume.