ABSTRACT

For each of the following scenarios, select the autoantibody that is most specific. Each option may be used once, more than once or not at all.

1. A 47-year-old woman complains that the skin of her fingers is becoming tight and it is becoming difficult for her to type. She is also having some problems swallowing. On examination, you notice that she has tight skin on both arms distal to the elbow and a furrowed mouth.