ABSTRACT
Eighty per cent of cases of MS have the relapsing and remitting type, 15% have a primary progressive course and 5% have fulminating disease with early death. The best investigation to demonstrate demyelination is MRI. Electrophoresis of cerebrospinal fluid shows oligoclonal bands of IgG immunoglobulin. High-dose steroids can shorten acute relapses of MS, but do not affect long-term outcome. Immunosuppressants and interferons reduce the number of relapses and improve outcome. Complications of MS include spasticity, ataxia, neuropathic pain and bladder dysfunction.
