ABSTRACT

Introduction 403 Complications of pregnancy 403 Potential mechanisms linking pregnancy complications

to coronary heart disease in later life 405

Clinical implications 406 Fetal programming 407 Conclusion 408 References 408

Considerable data link low birthweight due to intrauterine growth restriction (IUGR) to increased risk of vascular disease in the offspring’s later adult life. This is considered to be the result, in part, of programming through fetal nutrition.1