ABSTRACT
Lymphoma in pregnancy 971 Hodgkin lymphoma 971 Non-Hodgkin lymphoma 971 Staging 972 Radiation therapy during pregnancy 973 Chemotherapy during pregnancy 974 Pharmacokinetics in pregnancy 974 Effects of chemotherapy on the developing fetus 974 Management 975 Therapeutic abortion 975
Management of Hodgkin lymphoma 976 Management of Hodgkin lymphoma in early pregnancy 977 Management of Hodgkin lymphoma presenting after 977
the first trimester Management of non-Hodgkin lymphoma 978 Management of indolent lymphomas during pregnancy 979 Management of aggressive lymphomas during pregnancy 979 Management of lymphoma relapse during pregnancy 980 Key points 980 References 980
Although cancer is the leading cause of death in females of childbearing age,1 there is no evidence that incidence of cancers is higher during pregnancy. The incidence of cancer in pregnancy is estimated to be about 0.1 percent or approximately 1 in 1000 pregnancies.2,3 The most common malignancies diagnosed during pregnancy are those of breast, cervix, lymphoma, leukemia, cervix, ovary, and thyroid.4,5
Since most of the literature regarding cancer in pregnancy exists in the form of case reports, case series, or literature reviews, the important questions of effects of maternal cancer or effects of staging studies and therapy on fetus are not clearly answered. Whether pregnancy alters presentation, course, or prognosis of cancer in the mother is also largely unclear.
