ABSTRACT
Rhabdomyosarcoma (Greek rhabdo, ‘rod’; mys, ‘muscle’; sarkos, ‘flesh’) is a primary malignancy in children and adolescents that arises from embryonic mesenchyme, with the potential to differentiate into skeletal muscle. Wiener first described it in 1854, but it was not until the 1950s that the first series was reported, and Horn and Enterline described their histological classification, which is still used widely today.
