ABSTRACT

Neoplastic liver masses may occur in children, but they are uncommon. Figure 46.1 illustrates a simplified classification of the nature of the lesions that can present as liver masses. The most common benign lesions are typically of vascular

origin, are usually incidental and may not need specific treatment. Malignant liver tumours make up only two per cent of all cancers in the USA, the UK and Western Europe in this age group. There are two related but distinct malignant variants that occur with any degree of regularity: hepatoblastoma (HB) and hepatocellular carcinoma (HCC). HB is similar in its behaviour, relationship to genetic anomalies and good

• To understand the differential diagnosis of liver lesions in childhood. • To gain a working knowledge of common liver tumours. • To understand the diagnostic work-up of a child with an abdominal mass. • To gain a basic understanding of the segmental anatomy of the liver.