ABSTRACT

Molecular biology is no longer a revolution in medicine. It is now the very fabric of clinical practice and this is particularly so in the practice of oncology.

Understanding of the molecular processes underlying cancer, whether for prevention, diagnosis, treatment or palliation, is essential for the practitioner. The purpose of this chapter is twofold: first, to describe the concepts and language underlying this discipline, and second, to integrate these concepts into a clinical overview of where molecular biology currently impacts cancer treatment.