ABSTRACT

The occurrence of seizures in the neonate raises a number of concerns relating both to the neuroscience of epileptogenesis in the immature and to clinical issues of diagnosis and management. Although seizures in the neonate have been the topic of considerable basic and clinical investigations for some time and more intensively in recent years, there still remain considerable gaps in knowledge that require the clinician to develop management strategies with limited established data. These areas relate to diagnosis, pathophysiology, etiology, therapy and prognosis.