ABSTRACT

Case Presentation ...................................................................................................245 Differential Diagnosis ............................................................................................245 Treatment Strategies ..............................................................................................246 Long-Term outcome ...............................................................................................248 Neurobiology .........................................................................................................249 Clinical Pearls ........................................................................................................249 Suggested Reading .................................................................................................250

This patient had a single unprovoked generalized tonic-clonic seizure, in the context of sitting in front of a computer, with possible drowsiness. The computer raises the possibility of photic sensitivity, which can be seen with generalized epilepsy syndromes. However, the patient did complain of dizziness prior to the onset of her generalized tonic-clonic seizure. This could represent a simple partial seizure (i.e., aura) followed by secondary generalization. Alternatively, this could imply that the patient had a brief series of generalized 3-4 Hz spike-and-slow-wave discharges, which in