ABSTRACT

A. Introduction Strategies for treating most cancers usually employ surgical resection, chemotherapy, and/or radiation therapy. Although surgical resection can be very effective and sometimes curative in localized tumors, the presence of distant sites or inoperable tumors leaves the options of chemotherapy and/or radiotherapy. If chemotherapeutic drugs or radiotherapy could be selectively delivered to tumors, it would be possible to avoid, or at least reduce, unwanted toxicity and improve efficacy (1).