ABSTRACT
The first point of contact of microbial pathogens entering the lungs are the epithelial cells that line the airways and alveoli, and the lining fluid that bathes their apical surface. Lung epithelial cells constitutively
Table 2 Infectious Etiologies of Pulmonary Infiltrates Associated with Specific Immune Defects: Deficiencies of Local Defenses
Type of microorganism
Associated conditions Bacterial Fungal Viral
Mucositis Streptoccoccus spp. Aspergillus Herpes simplex Altered glottic function Staphylococcus spp. Candida Varicella-zoster Indwelling catheters Pseudomonas spp. Mucoraceae Endotracheal tubes Enterobacteriaceae Fusaria Venipunctures Corynebacterium
Table 3 Infectious Etiologies of Pulmonary Infiltrates Associated with Specific Immune Defects: Deficiencies in Innate Immunity
Type of microorganism
Defect Associated conditions Bacterial Fungal
Neutrophil disorder Neutropenia Mucositis Psuedomonas aerginosa Aspergillus
Acute leukemia Staphylococcus aureus Candida Hodgkin’s lymphoma Coagulase negative staphylococci Mucoraceae Tumor infiltration of BM Viridans streptococci Fusaria Infectious=infiltration of BM Enterobacteria Cryptococcus Chemotherapy Corynebacterium jeikeium Pseudoallescheria spp. Radiation therapy Enterococci Histoplasma spp.
